Day 1 – 6 March 2012

• The global value chain for TB diagnostics and current pipeline (by M Pai) [Slides]
• Value chain in action: Xpert MTB/RIF (by M Nicol) [Slides]
• Beyond Xpert: What will the future look like? (by K Dheda) [Slides]
• Value chain in action: TB serological tests (by M Pai) [Slides]
• Types of diagnostic designs and landscape of TB dx research (by M Pai) [Slides]
• Evaluation of reproducibility and reliability of TB diagnostics (by R van Zyl-Smit) [Slides]
• Incremental value of new diagnostics: an overview (by M Pai) [Slides]
• Incremental value: case study: IGRAs in HIV+ patients (by M Rangaka) [Slides]

Day 2 – 7 March 2012

• Impact of test results on diagnostic thinking and clinical decisions: an overview (by M Pai) [Slides]
• POC testing (by M Pai) [Slides]
• Reference standards: Brief presentations & panel discussion
  • Microscopy studies (by A Whitelaw) [Slides]
  • Molecular assays (by M Nicol) [Slides]
  • LTBI tests (by M Pai) [Slides]
  • Pediatric TB (by H Zar) [Slides]
  • Extrapulmonary TB (by J Peter) [Slides]
• Diagnosis of TB end-points in vaccine trials: methodological issues (by H Mahomed) [Slides]
• Evaluation of TB biomarkers: methodological issues (by W Hanekom) [Slides]
• Impact on patient outcomes: intro to diagnostic RCTs (by M Pai) [Slides]
• Diagnostic RCTs: case study: Xpert MTB/RIF (by G Theron) [Slides]

Day 3 – 8 March 2012

• Systematic reviews & meta-analyses of diagnostic accuracy (by M Pai) [Slides]
• SR: case study 1: Oral fluid vs blood-based HIV testing (by N Pant Pai) [Slides]
• SR: case study 2: Predictive value of IGRAs (by M Rangaka) [Slides]
• Guideline development in TB diagnostics (by M Pai) [Slides]
• Operational and implementation research: an overview (by M Pai) [Slides]
• Implementation research: case study 1: Improving case detection in HIV-infected persons (by S Lawn) [Slides]
• Implementation research: case study 2: Optimizing specimen collection in children (by H Zar) [Slides]
• Implementation research: case study 3: Optimizing urine-based diagnostics (by J Peter) [Slides]

Day 4 – 9 March 2012

• Modeling of TB diagnostics (by P Uys) [Slides]
• Cost-effectiveness analyses (by E Sinanovic) [Slides]
• Panel Discussion: Getting your study published! (by M Pai & K Dheda & S Lawn & R Wilkinson) [Slides]
• Raising funds and finding mentorship (by R Wilkinson) [Slides]