TB Research Methods – 14-18 July 2014
Montreal, Canada
The TB Research Methods course is an intensive course focused on molecular and genetic epidemiology, randomized controlled trials, diagnostic research, meta-analyses, decision analyses and modeling.
Course flyer
Course agendaDay 1 – 14 July 2014
- Overview – The WHO global TB research Plan (by C Leinhardt) [Slides]
- Research priorities in DR-TB (by D Menzies) [Slides]
- Pediatric TB research – barriers and progress (by B Marais) [Slides]
- HIV-TB research and global priorities (by WJ Burman) [Slides]
- Overview of study architectures (by D Menzies) [Slides]
Day 2 – 15 July 2014
- Operational research: what, why and how (by AD Harries) [Slides]
- Capacity building for operational research in low- and middle-income countries – the SORT IT Model (by AD Harries) [Slides]
- Principles and structure of a research protocol (by AD Harries) [Slides]
- Examples of operations research studies conducted within the Indian National TB Control Programme (by S Satyanarayana) [Slides]
- Error, Confounders and Bias (by M Pai) [Slides]
Day 3 – 16 July 2014
- Molecular methods for typing and branding the tubercle bacillus (by M Behr) [Slides]
- Molecular Typing for patient, outbreak and population-level studies of TB epidemiology (by M Behr) [Slides]
- Genetic Epidemiology – A brief introduction (by E Schurr) [Slides]
- Genetic association studies in TB (by E Schurr) [Slides]
- Population selection and sample size (by A Benedetti) [Slides]
Day 4 – 17 July 2014
- Trial designs. Phase 1, 2 and 3 trials. Pragmatic and OBT designs (by D Menzies) [Slides]
- Study populations and sample size. Recruitment and randomization. Preventing bias and measurement issues (by F Ahmad Khan) [Slides]
- Details re Cluster Randomized and stepped intervention trials. Safety and ethics in trials. Adverse events and DSMB. Study oversight (by G Fox) [Slides]
- Data Analysis – primary end-points, planned and unplanned secondary analyses. Interim analyses, stopping rules (by D Menzies) [Slides]
- Data Analysis Methodology (by A Benedetti) [Slides]
Day 5 – 18 July 2014
- Introduction to infectious disease modeling (by O Oxlade) [Slides]
- Introduction to economic analyses (by K Schwartzman) [Slides]
- How to evaluate an economic analysis (by K Schwartzman) [Slides]
- Issues and challenges in modeling TB (by O Oxlade) [Slides]
|

|